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Anti-PON2 Antibody

     
  • WB - Anti-PON2 Antibody ABO11564
    Anti-PON2 antibody, ABO11564, All Western blottingAll lanes: Anti-PON2(ABO11564) at 0.5ug/mlLane 1: Rat Liver Tissue Lysate at 40ugLane 2: Rat Lung Tissue Lysate at 40ugLane 3: Human Placenta Tissue Lysate at 40ugLane 4: Rat Testis Tissue Lysate at 40ugLane 5: HELA Whole Cell Lysate at 40ugLane 6: HEPA Whole Cell Lysate at 40ugLane 7: A549 Whole Cell Lysate at 40ugLane 8: JURKAT Whole Cell Lysate at 40ugLane 9: SKOV Whole Cell Lysate at 40ugPredicted bind size: 39KDObserved bind size: 39KD
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q15165
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Serum paraoxonase/arylesterase 2(PON2) detection. Tested with WB in Human;Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 5445
Other Names Serum paraoxonase/arylesterase 2, PON 2, 3.1.1.2, 3.1.1.81, Aromatic esterase 2, A-esterase 2, Serum aryldialkylphosphatase 2, PON2
Calculated MW 39397 MW KDa
Application Details Western blot, 0.1-0.5 µg/ml, Human, Mouse, Rat
Subcellular Localization Membrane ; Peripheral membrane protein .
Tissue Specificity Widely expressed with highest expression in liver, lung, placenta, testis and heart. .
Protein Name Serum paraoxonase/arylesterase 2
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human PON2(189-203aa FLKYLETYLNLHWAN), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Sequence Similarities Belongs to the paraoxonase family.
Protein Information
Name PON2
Function Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
Cellular Location Membrane; Peripheral membrane protein
Tissue Location Widely expressed with highest expression in liver, lung, placenta, testis and heart.
Research Areas
Citations (0)
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Background

PON2 is an enzyme that in humans is encoded by the PON2 gene. This gene is mapped to 7q21.3. This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones and important bacterial quorum-sensing mediators suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. 

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$ 240.00
Cat# ABO11564
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