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Anti-XCL1/Lymphotactin Antibody

     
  • WB - Anti-XCL1/Lymphotactin Antibody ABO12367
    Anti- Lymphotactin Picoband antibody, ABO12367, Western blottingAll lanes: Anti Lymphotactin (ABO12367) at 0.5ug/mlWB: HELA Whole Cell Lysate at 40ugPredicted bind size: 13KDObserved bind size: 13KD
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P47992
Host Rabbit
Reactivity Human
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Lymphotactin(XCL1) detection. Tested with WB, ELISA(Cap) in Human.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 6375
Other Names Lymphotactin, ATAC, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1, XC chemokine ligand 1, XCL1, LTN, SCYC1
Calculated MW 12517 MW KDa
Application Details Western blot, 0.1-0.5 µg/ml, Human

ELISA(Cap), 0.1-0.5 µg/ml
Subcellular Localization Secreted.
Tissue Specificity Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.
Protein Name Lymphotactin
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen E.coli-derived human Lymphotactin recombinant protein (Position: V22-G114). Human Lymphotactin shares 60.2% and 57% amino acid (aa) sequence identity with mouse and rat Lymphotactin, respectively.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Information
Name XCL1
Synonyms LTN, SCYC1
Function Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Cellular Location Secreted.
Tissue Location Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine
Research Areas
Citations (0)
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Background

Chemokine (C motif) ligand (XCL1) is a small cytokine belonging to the XC chemokine family that is also known as lymphotactin. Muller et al. (1995) mapped the gene to chromosome 1q23 by FISH. The sequence of the deduced 114-amino acid protein is most homologous to the CC chemokines CCL8 and CCL3. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. XCL1 induces the migration of cells expressing XCR1.

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$ 240.00
Cat# ABO12367
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