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4-1BBR Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q07011 |
| Other Accession | NP_001552 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 27899 Da |
| Gene ID | 3604 |
|---|---|
| Application & Usage | Western Blot analysis (0.5-2.0 µg/ml). Per researcher’s feedback, it can also be used in Neutralization (2-4 µg/ml). However, the optimal conditions should be determined individually. |
| Other Names | 4-1BB Receptor |
| Target/Specificity | 4-1BBR |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-human 4-1BBR polyclonal antibody in PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | 4-1BBR Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TNFRSF9 |
|---|---|
| Synonyms | CD137, ILA |
| Function | Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed on the surface of activated T-cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Human 4-1BB Receptor (4-1BBR) is an inhibitor of 4-1BBL and can block 4-1BBL bioactivity. Human 4-1BBR is a 17.7 kDa protein containing 167 amino acid residues.
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