PlGF Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P49764 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 17876 Da |
Gene ID | 18654 |
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Application & Usage | Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been determined. |
Other Names | PIGF1, PIGF 1, PIGF-1, Phosphatidylinositol glycan biosynthesis class F, PIG F |
Target/Specificity | PIGF |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | PlGF Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Pgf |
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Synonyms | Plgf |
Function | Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Also promotes cell tumor growth (By similarity). |
Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PLGF (also called Placenta Growth Factor, PIGF, PGF) is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF is expressed in placental tissues, colon and mammary carcinomas. It signals thro µgh the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant mouse PLGF is a disulfide-linked homodimer containing two 142 amino acid polypeptide chains.
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