Functional BAFF-R (mouse) Antibody, mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC |
---|---|
Primary Accession | Q9D8D0 |
Reactivity | Mouse |
Host | Purified From Concentrated Hybridoma Tissue Culture Supernatant. |
Clonality | Monoclonal |
Isotype | Rat IgG2b |
Gene Source | Mouse |
Endotoxin | <0.01EU/ µg purified protein (LAL test; Lonza). |
Application Note | FC,Functional Application, Depletion of B cells in vivo, |
Clone Names | 9B9 |
Calculated MW | 18798 Da |
Gene ID | 72049 |
---|---|
Other Names | BAFF Receptor; BR3; BlySR3; CD268; TNFRSF13C |
Target/Specificity | Recognizes mouse BAFF-R. |
Format | Liquid. In PBS containing 0.02% sodium azide. |
Reconstitution & Storage | Stable for at least 1 year after receipt when stored at -20°C. |
Precautions | Functional BAFF-R (mouse) Antibody, mAb is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Tnfrsf13c |
---|---|
Synonyms | Baffr, Bcmd, Br3 |
Function | B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. |
Cellular Location | Membrane; Single-pass type III membrane protein |
Tissue Location | Highly expressed in spleen and testis; detected at lower levels in lung and thymus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.
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