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XCL1 / XCL2 Antibody (internal region)

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E
Primary Accession P47992
Other Accession NP_002986.1, NP_003166.1, 6375
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 12517 Da
Additional Information
Gene ID 6375
Other Names Lymphotactin, ATAC, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1, XC chemokine ligand 1, XCL1, LTN, SCYC1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsXCL1 / XCL2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name XCL1
Synonyms LTN, SCYC1
Function Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Cellular Location Secreted.
Tissue Location Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine
Research Areas
Citations (0)
citation

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Background

XCL1 and CXL2 are almost identical and therefore this antibody is expected to recognize both proteins.

References

Interconversion between two unrelated protein folds in the lymphotactin native state. Tuinstra RL, Peterson FC, Kutlesa S, Elgin ES, Kron MA, Volkman BF, Proc. Natl. Acad. Sci. U.S.A. 2008 Apr 105 (13): 5057-62. PMID: 18364395

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$ 216.00
Cat# AF2916a
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