COL4A6 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q14031 |
Other Accession | NP_001838.2, NP_378667.1, 1288 |
Predicted | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 163807 Da |
Gene ID | 1288 |
---|---|
Other Names | Collagen alpha-6(IV) chain, COL4A6 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | COL4A6 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | COL4A6 |
---|---|
Function | Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. |
Cellular Location | Secreted, extracellular space, extracellular matrix, basement membrane |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize both reported isoforms (NP_001838.2; NP_378667.1).
References
Structure of the human type IV collagen COL4A6 gene, which is mutated in Alport syndrome-associated leiomyomatosis Zhang X, Zhou J, Reeders ST, Tryggvason K Genomics. 1996 May 33 (3): 473-9. PMID: 8661006
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