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Cone-rod homeobox (C Terminus) Antibody (internal region, near C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O43186 |
| Other Accession | NP_000545.1, 1406, 12951 (mouse), 60446 (rat) |
| Reactivity | Rat |
| Predicted | Human, Mouse, Pig, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 32261 Da |
| Gene ID | 1406 |
|---|---|
| Other Names | Cone-rod homeobox protein, CRX, CORD2 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Cone-rod homeobox (C Terminus) Antibody (internal region, near C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CRX |
|---|---|
| Synonyms | CORD2 |
| Function | Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
| Tissue Location | Retina. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Immunohistochemical expression of CRX in extracranial malignant small round cell tumors. Terry J, Calicchio ML, Rodriguez-Galindo C, Perez-Atayde AR. The American journal of surgical pathology 2012 Aug 36 (8): 1165-9. PMID: 22790857
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