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HS3ST1 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O14792 |
| Other Accession | NP_005105.1, 9957 |
| Reactivity | Human |
| Predicted | Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 35773 Da |
| Gene ID | 9957 |
|---|---|
| Other Names | Heparan sulfate glucosamine 3-O-sulfotransferase 1, 2.8.2.23, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1, 3-OST-1, Heparan sulfate 3-O-sulfotransferase 1, h3-OST-1, HS3ST1, 3OST, 3OST1 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HS3ST1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HS3ST1 |
|---|---|
| Synonyms | 3OST, 3OST1 |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan (PubMed:9346953, PubMed:8900198, PubMed:9988768). Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact) (PubMed:8900198, PubMed:9988768). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site (PubMed:8900198, PubMed:9988768). |
| Cellular Location | Golgi apparatus lumen. |
| Tissue Location | Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
A conformational change in heparan sulfate 3-O-sulfotransferase-1 is induced by binding to heparan sulfate. Edavettal SC, Carrick K, Shah RR, Pedersen LC, Tropsha A, Pope RM, Liu J. Biochemistry 2004 Apr 43 (16): 4680-8. PMID: 15096036
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