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SYMPK antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - SYMPK antibody - middle region AI12184

    WB Suggested Anti-SYMPK Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: HepG2 cell lysate
    SYMPK is supported by BioGPS gene expression data to be expressed in HepG2
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q92797
Other Accession NM_004819, NP_004810
Reactivity Human, Rat, Pig
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 141kDa
Additional Information
Gene ID 8189
Alias Symbol FLJ27092, SPK, SYM
Other Names Symplekin, SYMPK, SPK
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-SYMPK antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSYMPK antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SYMPK
Synonyms SPK
Function Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing. Specific component of the tight junction (TJ) plaque, but might not be an exclusively junctional component. May have a house-keeping rule. Is involved in pre-mRNA polyadenylation. Enhances SSU72 phosphatase activity.
Cellular Location Cytoplasm, cytoskeleton. Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side Cell junction. Nucleus, nucleoplasm. Note=Cytoplasmic face of adhesion plaques (major) and nucleoplasm (minor) (in cells with TJ). Nucleoplasm (in cells without TJ). Nuclear bodies of heat-stressed cells Colocalizes with HSF1 in nuclear stress bodies upon heat shock (PubMed:14707147).
Tissue Location In testis, expressed in polar epithelia and Sertoli cells but not in vascular endothelia. The protein is detected in stomach, duodenum, pancreas, liver, fetal brain, carcinomas, lens- forming cells, fibroblasts, lymphocytes, lymphoma cells, erythroleukemia cells but not in endothelium of vessels, epidermis, intercalated disks, Purkinje fiber cells of the heart and lymph node
Research Areas
Citations (0)
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$ 389.00
Cat# AI12184
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