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ADAM2 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - ADAM2 antibody - N-terminal region AI13581

    WB Suggested Anti-ADAM2 Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Skin
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q99965
Other Accession NM_001464, NP_001455
Reactivity Human, Rat, Pig
Predicted Human, Rat, Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 81kDa
Additional Information
Gene ID 2515
Alias Symbol CRYN1, CRYN2, CT15, FTNB, PH-30b, PH30
Other Names Disintegrin and metalloproteinase domain-containing protein 2, ADAM 2, Cancer/testis antigen 15, CT15, Fertilin subunit beta, PH-30, PH30, PH30-beta, ADAM2, FTNB
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ADAM2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsADAM2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADAM2
Synonyms FTNB
Function Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
Cellular Location Membrane; Single-pass type I membrane protein.
Tissue Location Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues
Research Areas
Citations (0)
citation

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References

Vidaeus C.M.,et al.Mol. Reprod. Dev. 46:363-369(1997).
Gupta S.K.,et al.Biochem. Biophys. Res. Commun. 224:318-326(1996).
Burkin H.R.,et al.Genomics 40:190-192(1997).
Hall L.,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.

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$ 389.00
Cat# AI13581
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