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RAB2A antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - RAB2A antibody - C-terminal region AI14677
    RAB2A antibody - C-terminal region (AI14677) validated by WB using MDA-MB435S cell lysate
    at 1μg/ml.RAB2A is strongly supported by BioGPS gene expression data to be expressed in Human MDA-MB435 cells
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P61019
Other Accession NM_002865, NP_002856
Reactivity Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 23kDa
Additional Information
Gene ID 5862
Alias Symbol RAB2, LHX
Other Names Ras-related protein Rab-2A, RAB2A, RAB2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RAB2A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRAB2A antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB2A (HGNC:9763)
Synonyms RAB2
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Required for protein transport from the endoplasmic reticulum to the Golgi complex. Regulates the compacted morphology of the Golgi.
Cellular Location Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:P53994} Note=Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). {ECO:0000250|UniProtKB:P53994, ECO:0000269|PubMed:17081065}
Research Areas
Citations (0)
citation

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References

Tachibana K.,et al.Nucleic Acids Res. 16:10368-10368(1988).
Zahraoui A.,et al.J. Biol. Chem. 264:12394-12401(1989).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 389.00
Cat# AI14677
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