DNAJC7 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q99615 |
Other Accession | NM_003315, NP_003306 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 56kDa |
Gene ID | 7266 |
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Alias Symbol | DJ11, DJC7, TPR2, TTC2 |
Other Names | DnaJ homolog subfamily C member 7, Tetratricopeptide repeat protein 2, TPR repeat protein 2, DNAJC7, TPR2, TTC2 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-DNAJC7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | DNAJC7 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DNAJC7 |
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Synonyms | TPR2, TTC2 |
Function | Acts as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm (By similarity). |
Cellular Location | Cytoplasm. Nucleus Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9QYI3} Note=Colocalizes with NR1I3 to microtubules {ECO:0000250|UniProtKB:Q9QYI3} |
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Provided below are standard protocols that you may find useful for product applications.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (MAR-2009) to UniProtKB.
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