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HPSE2 Antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - HPSE2 Antibody - N-terminal region AI15285

    WB Suggested Anti-HPSE2 Antibody Titration: 1.0 μg/ml
    Positive Control: Jurkat Whole Cell
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q8WWQ2
Other Accession NM_001166245, NP_001159717
Reactivity Human, Mouse, Dog
Predicted Human, Mouse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Additional Information
Gene ID 60495
Alias Symbol FLJ11684, FLJ44022, HPA2, HPR2, MGC133234
Other Names Inactive heparanase-2, Hpa2, HPSE2, HPA2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-HPSE2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHPSE2 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HPSE2
Synonyms HPA2
Function Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Widely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus. In the central nervous system, expressed in the spinal chord, caudate nucleus, thalamus, substantia nigra, medulla oblongata, putamen and pons. In the urinary bladder, expressed in longitudinal and circular layers of detrusor muscle. Found both in normal and cancer tissues
Research Areas
Citations (0)
citation

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References

McKenzie E.,et al.Biochem. Biophys. Res. Commun. 276:1170-1177(2000).
Legoux P.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 429:375-381(2004).
Pang J.,et al.Am. J. Hum. Genet. 86:957-962(2010).
Pang J.,et al.Am. J. Hum. Genet. 87:161-161(2010).

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$ 389.00
Cat# AI15285
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