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ADCYAP1R1 / PAC1 Receptor Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - ADCYAP1R1 / PAC1 Receptor Antibody (N-Terminus) ALS10215
    Anti-ADCYAP1R1 antibody ALS10215 IHC of human placenta.
    detail
  • IHC - ADCYAP1R1 / PAC1 Receptor Antibody (N-Terminus) ALS10215
    Anti-ADCYAP1R1 antibody ALS10215 IHC of human heart.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession P41586
Reactivity Human, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Dilution IHC-P (5-7 µg/ml)
Additional Information
Gene ID 117
Other Names Pituitary adenylate cyclase-activating polypeptide type I receptor, PACAP type I receptor, PACAP-R-1, PACAP-R1, ADCYAP1R1
Target/Specificity Human ADCYAP1R1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsADCYAP1R1 / PAC1 Receptor Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADCYAP1R1
Function This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.

References

Ogi K.,et al.Biochem. Biophys. Res. Commun. 196:1511-1521(1993).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
King M.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).

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Discontinued
Cat# ALS10215
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