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EDA2R / XEDAR Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q9HAV5 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 33kDa |
| Dilution | IHC-P (2.5 µg/ml) |
| Gene ID | 60401 |
|---|---|
| Other Names | Tumor necrosis factor receptor superfamily member 27, X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, TNFRSF27, XEDAR |
| Target/Specificity | Human EDA2R, antibody does not detect mouse EDA2R |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | EDA2R / XEDAR Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EDA2R |
|---|---|
| Synonyms | TNFRSF27, XEDAR |
| Function | Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6. |
| Cellular Location | Membrane; Single-pass type III membrane protein. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.
References
Yan M.,et al.Science 290:523-527(2000).
Sinha S.K.,et al.J. Biol. Chem. 277:44953-44961(2002).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ross M.T.,et al.Nature 434:325-337(2005).
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