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CRLF2 / TSLPR Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IF - CRLF2 / TSLPR Antibody (Internal) ALS12690
    Immunofluorescence of TSLP Receptor in Human Liver cells with TSLP Receptor antibody at 20 ug/ml.
    detail
  • IHC - CRLF2 / TSLPR Antibody (Internal) ALS12690
    Anti-CRLF2 antibody IHC of human liver.
    detail
  • WB - CRLF2 / TSLPR Antibody (Internal) ALS12690
    Western blot of TSLP Receptor in human liver tissue lysate with ALS12690 at (A) 0.5, (B) 1 and...
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9HC73
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 42kDa
Dilution IHC-P (5 µg/ml), WB (1 µg/ml),
Additional Information
Gene ID 64109
Other Names Cytokine receptor-like factor 2, Cytokine receptor-like 2, IL-XR, Thymic stromal lymphopoietin protein receptor, TSLP receptor, CRLF2, CRL2, ILXR, TSLPR
Target/Specificity a 19 amino acid peptide from near the center of human TSLP-R
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsCRLF2 / TSLPR Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRLF2
Synonyms CRL2, ILXR, TSLPR
Function Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.
Cellular Location [Isoform 1]: Cell membrane; Single- pass type I membrane protein
Tissue Location Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes Weakly expressed in T-cells
Research Areas
Citations (0)
citation

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Background

Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.

References

Zhang W.,et al.Biochem. Biophys. Res. Commun. 281:878-883(2001).
Tonozuka Y.,et al.Cytogenet. Cell Genet. 93:23-25(2001).
Reche P.A.,et al.J. Immunol. 167:336-343(2001).
Li T.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 467.50
Cat# ALS12690
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