ZNF536 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | O15090 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 141kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 9745 |
---|---|
Other Names | Zinc finger protein 536, ZNF536, KIAA0390 |
Target/Specificity | Human ZNF536 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | ZNF536 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ZNF536 |
---|---|
Synonyms | KIAA0390 |
Function | Transcriptional repressor that negatively regulates neuron differentiation by repressing retinoic acid-induced gene transcription (PubMed:19398580). Binds and interrupts RARA from binding to retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (PubMed:19398580). Recognizes and binds 2 copies of the core DNA sequence 5'-CCCCCA-3' (PubMed:14621294). |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May be involved in transcriptional regulation. Recognizes and binds 2 copies of the core DNA sequence 5'-CCCCCA- 3'.
References
Nagase T.,et al.DNA Res. 4:141-150(1997).
Ohara O.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Sakai T.,et al.DNA Res. 10:155-165(2003).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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