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HSPB6 / HSP20 Antibody (aa5-54)

Rabbit Polyclonal Antibody

     
  • IHC - HSPB6 / HSP20 Antibody (aa5-54) ALS14723
    Anti-HSPB6 antibody IHC of human skeletal muscle.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession O14558
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 17kDa
Dilution ELISA (1:5000), IHC-P (10 µg/ml),
Additional Information
Gene ID 126393
Other Names Heat shock protein beta-6, HspB6, Heat shock 20 kDa-like protein p20, HSPB6
Target/Specificity HSPB6 antibody detects endogenous levels of total HSPB6 protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsHSPB6 / HSP20 Antibody (aa5-54) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSPB6
Function Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.
Cellular Location Cytoplasm. Nucleus. Secreted Note=Translocates to nuclear foci during heat shock
Volume 50 µl
Research Areas
Citations (0)
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References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Kato K.,et al.J. Biol. Chem. 269:15302-15309(1994).
Vos M.J.,et al.Biochim. Biophys. Acta 1793:1343-1353(2009).

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Discontinued
Cat# ALS14723
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