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KIAA1324 / maba1 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • ICC - KIAA1324 / maba1 Antibody (C-Terminus) ALS14830
    Immunocytochemistry of EIG121 in MCF7 cells with EIG121 antibody at 5 ug/ml.
    detail
  • IF - KIAA1324 / maba1 Antibody (C-Terminus) ALS14830
    Immunofluorescence of EIG121 in MCF7 cells with EIG121 antibody at 20 ug/ml.
    detail
  • WB - KIAA1324 / maba1 Antibody (C-Terminus) ALS14830
    Western blot analysis of EIG121 in MCF7 cell lysate with EIG121 antibody at 1 ug/ml in (A) the...
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, ICC
Primary Accession Q6UXG2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 111kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 57535
Other Names UPF0577 protein KIAA1324, Estrogen-induced gene 121 protein, KIAA1324, EIG121
Target/Specificity Human KIAA1324. At least four isoforms of EIG121 known to exist. EIG121 antibody is predicted to not cross-react with other UPF0577 protein family members.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsKIAA1324 / maba1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ELAPOR1 (HGNC:29618)
Function May protect cells from cell death by inducing cytosolic vacuolization and up-regulating the autophagy pathway (PubMed:21072319). May play a role in apoptosis and cell proliferation through its interaction with HSPA5 (PubMed:26045166).
Cellular Location Cell membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein
Tissue Location Expressed in normal endometrium but overexpressed in endometroid tumors.
Research Areas
Citations (0)
citation

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Background

May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway.

References

Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Gregory S.G.,et al.Nature 441:315-321(2006).
Nagase T.,et al.DNA Res. 7:65-73(2000).
Deng L.,et al.Clin. Cancer Res. 11:8258-8264(2005).
Deng L.,et al.Cell Death Dis. 1:E32-E32(2010).

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$ 467.50
Cat# ALS14830
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