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PLD1 / Phospholipase D1 Antibody (aa527-576)

Rabbit Polyclonal Antibody

     
  • IHC - PLD1 / Phospholipase D1 Antibody (aa527-576) ALS15074
    Anti-PLD1 antibody IHC of human spleen.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q13393
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 124kDa
Dilution ELISA (1:1000), IHC-P (10 µg/ml),
Additional Information
Gene ID 5337
Other Names Phospholipase D1, PLD 1, hPLD1, 3.1.4.4, Choline phosphatase 1, Phosphatidylcholine-hydrolyzing phospholipase D1, PLD1
Target/Specificity PLD1 Antibody detects endogenous levels of total PLD1 protein.
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsPLD1 / Phospholipase D1 Antibody (aa527-576) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLD1 (HGNC:9067)
Function Function as phospholipase selective for phosphatidylcholine (PubMed:8530346, PubMed:9582313, PubMed:25936805). Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).
Cellular Location Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9Z280}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9Z280}; Lipid-anchor {ECO:0000250|UniProtKB:Q9Z280}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9Z280}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9Z280}; Lipid-anchor {ECO:0000250|UniProtKB:Q9Z280}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9Z280}. Late endosome membrane {ECO:0000250|UniProtKB:Q9Z280}; Lipid-anchor {ECO:0000250|UniProtKB:Q9Z280}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9Z280}
Tissue Location Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).

References

Hammond S.M.,et al.J. Biol. Chem. 270:29640-29643(1995).
Hammond S.M.,et al.J. Biol. Chem. 272:3860-3868(1997).
Steed P.M.,et al.FASEB J. 12:1309-1317(1998).
Hughes W.E.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Lopez I.,et al.J. Biol. Chem. 273:12846-12852(1998).

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$ 467.50
Cat# ALS15074
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