SPTAN1 / Alpha Fodrin Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, ICC |
---|---|
Primary Accession | Q13813 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 285kDa |
Dilution | ICC (1:500-1:1000), IF (1:500-1:1000), IHC-P (1:100), WB (1:5000-1:10000) , |
Gene ID | 6709 |
---|---|
Other Names | Spectrin alpha chain, non-erythrocytic 1, Alpha-II spectrin, Fodrin alpha chain, Spectrin, non-erythroid alpha subunit, SPTAN1, NEAS, SPTA2 |
Target/Specificity | Human SPTAN1 / Alpha Fodrin |
Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
Precautions | SPTAN1 / Alpha Fodrin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SPTAN1 |
---|---|
Synonyms | NEAS, SPTA2 |
Function | Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. |
Cellular Location | Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
References
Moon R.T.,et al.J. Biol. Chem. 265:4427-4433(1990).
Cianci C.D.,et al.Biochemistry 38:15721-15730(1999).
Kato S.,et al.Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
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