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SPTAN1 / Alpha Fodrin Antibody

Rabbit Polyclonal Antibody

     
  • ICC - SPTAN1 / Alpha Fodrin Antibody ALS16112
    Mixed neuron-glial cultures stained with rabbit antibody to alpha-II spectrin (green) and mouse...
    detail
  • IHC - SPTAN1 / Alpha Fodrin Antibody ALS16112
    Anti-SPTAN1 / Alpha Fodrin antibody IHC staining of human small intestine, submucosal plexus.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, ICC
Primary Accession Q13813
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 285kDa
Dilution ICC (1:500-1:1000), IF (1:500-1:1000), IHC-P (1:100), WB (1:5000-1:10000) ,
Additional Information
Gene ID 6709
Other Names Spectrin alpha chain, non-erythrocytic 1, Alpha-II spectrin, Fodrin alpha chain, Spectrin, non-erythroid alpha subunit, SPTAN1, NEAS, SPTA2
Target/Specificity Human SPTAN1 / Alpha Fodrin
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsSPTAN1 / Alpha Fodrin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPTAN1
Synonyms NEAS, SPTA2
Function Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.

References

Moon R.T.,et al.J. Biol. Chem. 265:4427-4433(1990).
Cianci C.D.,et al.Biochemistry 38:15721-15730(1999).
Kato S.,et al.Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).

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Discontinued
Cat# ALS16112
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