CDC42EP2 Antibody (aa10-59)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | O14613 |
Other Accession | 10435 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 22484 Da |
Dilution | ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000), |
Gene ID | 10435 |
---|---|
Other Names | CDC42EP2, Binder of Rho GTPases 1, BORG1, Cdc42 effector protein 2, CRIB-containing BOGR1 protein, CEP2 |
Target/Specificity | BORG1 Antibody detects endogenous levels of total BORG1 protein. |
Reconstitution & Storage | PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year. |
Precautions | CDC42EP2 Antibody (aa10-59) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CDC42EP2 |
---|---|
Synonyms | BORG1, CEP2 |
Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner. |
Cellular Location | Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton |
Tissue Location | Highly expressed in the heart. Weakly expressed in the pancreas and liver. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
References
Guru S.C.,et al.Genome Res. 7:725-735(1997).
Joberty G.,et al.Mol. Cell. Biol. 19:6585-6597(1999).
Hirsch D.S.,et al.J. Biol. Chem. 276:875-883(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
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