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SNTA1 / Syntrophin Alpha 1 Antibody (aa191-505)

Rabbit Polyclonal Antibody

     
  • IHC - SNTA1 / Syntrophin Alpha 1 Antibody (aa191-505) ALS16918
    Anti-SNTA1 / Syntrophin Alpha 1 antibody IHC staining of human brain, cortex.
    detail
  • ICC - SNTA1 / Syntrophin Alpha 1 Antibody (aa191-505) ALS16918
    Immunofluorescence of methanol-fixed A549 using Syntrophin alpha 1 antibody at 1:500 dilution.
    detail
  • WB - SNTA1 / Syntrophin Alpha 1 Antibody (aa191-505) ALS16918
    Sample (30 ug of whole cell lysate).
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession Q13424
Other Accession 6640
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 53895 Da
Dilution ICC (1:100 - 1:1000), IHC-P (7.5 µg/ml), WB (1:1000 - 1:10000),
Additional Information
Gene ID 6640
Other Names SNTA1, Acidic alpha 1 syntrophin, DJ1187J4.5, Alpha-1-syntrophin, SNT1, Syntrophin Alpha 1, Syntrophin, alpha 1, Syntrophin-1, LQT12, TACIP1
Target/Specificity Human SNTA1 / Syntrophin Alpha 1
Reconstitution & Storage 0.1 M Tris-glycine, pH 7.0, 20% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsSNTA1 / Syntrophin Alpha 1 Antibody (aa191-505) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNTA1
Synonyms SNT1
Function Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate (By similarity).
Cellular Location Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell junction. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions
Tissue Location High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5- bisphosphate (By similarity).

References

Ahn A.H.,et al.J. Biol. Chem. 271:2724-2730(1996).
Castello A.,et al.FEBS Lett. 383:124-128(1996).
Hasegawa M.,et al.J. Biol. Chem. 274:12626-12631(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).

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Discontinued
Cat# ALS16918
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