BACH1 Antibody (aa134-421)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | O14867 |
Other Accession | 571 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 81958 Da |
Dilution | IHC-P (10 µg/ml), |
Gene ID | 571 |
---|---|
Other Names | BACH1, BTB and CNC homolog 1, HA2303, BACH-1 |
Target/Specificity | Human BACH1 |
Reconstitution & Storage | PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
Precautions | BACH1 Antibody (aa134-421) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BACH1 {ECO:0000303|PubMed:9544839, ECO:0000312|HGNC:HGNC:935} |
---|---|
Function | Transcriptional regulator that acts as a repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Plays important roles in coordinating transcription activation and repression by MAFK (By similarity). Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway (PubMed:24035498). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:24035498} |
Volume | 100 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.
References
Blouin J.-L.,et al.Hum. Genet. 102:282-288(1998).
Ohira M.,et al.Genomics 47:300-306(1998).
Taudien S.,et al.Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
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