Anti-CLDN4 / Claudin 4 Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | O14493 |
Predicted | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 22077 Da |
Dilution | IHC-P (5 µg/ml) |
Gene ID | 1364 |
---|---|
Alias Symbol | CLDN4 |
Other Names | CLDN4, Claudin-4, CPE-receptor, CPETR, CPETR1, Claudin 4, CPE-R, HCPE-R, WBSCR8, CPER |
Target/Specificity | c-terminal |
Reconstitution & Storage | Affinity purified |
Precautions | Anti-CLDN4 / Claudin 4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CLDN4 |
---|---|
Function | Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. |
Cellular Location | Cell junction, tight junction {ECO:0000250|UniProtKB:O35054}. Cell membrane; Multi-pass membrane protein. Note=CLDN4 is required for tight junction localization in the kidney. {ECO:0000250|UniProtKB:O35054} |
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