Anti-Betaglycan / TGFBR3 Antibody (Extracellular Domain, clone D11G10)
Rabbit Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IP |
---|---|
Primary Accession | Q03167 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal |
Isotype | IgG |
Clone Names | D11G10 |
Calculated MW | 93499 Da |
Dilution | IHC-P (1:100), IP (1:50), WB (1:1000) |
Gene ID | 7049 |
---|---|
Alias Symbol | TGFBR3 |
Other Names | TGFBR3, Betaglycan, BGCAN, TGF-beta receptor type 3, TGF-beta receptor type III, TGFR-3, Betaglycan proteoglycan, Tgf-beta receptors type iii |
Target/Specificity | Endogenous levels of total TGF-b receptor III. |
Reconstitution & Storage | Purified |
Precautions | Anti-Betaglycan / TGFBR3 Antibody (Extracellular Domain, clone D11G10) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TGFBR3 (HGNC:11774) |
---|---|
Function | Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors (By similarity). In gonadotrope cells, acts as an inhibin A coreceptor and regulates follicle-stimulating hormone (FSH) levels and female fertility (PubMed:34910520). |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P26342}; Single-pass type I membrane protein. Secreted {ECO:0000250|UniProtKB:P26342}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P26342}. Note=Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. {ECO:0000250|UniProtKB:P26342} |
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