Anti-IDO2 / INDOL1 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
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Primary Accession | Q6ZQW0 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 45424 Da |
Dilution | IHC-P (1:50), WB (1:500 - 1:1000) |
Gene ID | 169355 |
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Alias Symbol | IDO2 |
Other Names | IDO2, IDO-2, Indoleamine 2, 3-dioxygenase 2, INDOL1 |
Target/Specificity | Recognizes endogenous levels of IDO2 protein. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-IDO2 / INDOL1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | IDO2 (HGNC:27269) |
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Function | Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance (PubMed:25691885). |
Tissue Location | Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon (PubMed:17671174) Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%) (PubMed:25691885) |
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