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EPO Antibody (Ascites)
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P01588 |
| Other Accession | NP_000790.2 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgM |
| Clone/Animal Names | 511CT20.2.4 |
| Calculated MW | 21307 Da |
| Gene ID | 2056 |
|---|---|
| Other Names | Erythropoietin, Epoetin, EPO |
| Target/Specificity | Purified His-tagged EPO protein(Fragment) was used to produced this monoclonal antibody. |
| Dilution | WB~~1:1000~16000 |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | EPO Antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EPO |
|---|---|
| Function | Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. |
| Cellular Location | Secreted. |
| Tissue Location | Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq].
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kristensen, P.L., et al. Eur. J. Endocrinol. 163(3):391-398(2010)
Kim, M.H., et al. Mol. Biol. (Mosk.) 44(4):656-663(2010)
Carraway, M.S., et al. Circ. Res. 106(11):1722-1730(2010)
Shi, Z., et al. Mol. Cancer Res. 8(4):615-626(2010)
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