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HTR3A
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC, E |
|---|---|
| Primary Accession | P46098 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 3B11C10 |
| Isotype | Mouse IgG2a |
| Calculated MW | 55.3kDa |
| Immunogen | Purified recombinant fragment of human HTR3A (AA: extra 24-157) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 3359 |
|---|---|
| Other Names | HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R |
| Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 FCM~~1/200 - 1/400 ICC~~ 1/100 - 1/500 IHC~~ 1/200 - 1/1000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HTR3A is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HTR3A (HGNC:5297) |
|---|---|
| Synonyms | 5HT3R, HTR3 |
| Function | Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation- selective channel complexes, which when activated cause fast, depolarizing responses in neurons. |
| Cellular Location | Postsynaptic cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P23979}. Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P23979} |
| Tissue Location | Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
1.PLoS One. 2015 Dec 23;10(12):e0145269.2.Iran J Allergy Asthma Immunol. 2014 Feb;13(1):33-9.
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