CD102
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC, E |
---|---|
Primary Accession | P13598 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 6B9G10 |
Isotype | Mouse IgG1 |
Calculated MW | 30.7kDa |
Immunogen | Purified recombinant fragment of human CD102 (AA: extra 25-223) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Gene ID | 3384 |
---|---|
Other Names | ICAM2 |
Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 FCM~~1/200 - 1/400 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CD102 is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ICAM2 |
---|---|
Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. |
Cellular Location | Membrane; Single-pass type I membrane protein. Cell projection, microvillus {ECO:0000250|UniProtKB:P35330}. Note=Co-localizes with RDX, EZR and MSN in microvilli. {ECO:0000250|UniProtKB:P35330} |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Curr Opin Hematol. 2015 Jan;22(1):53-9. 2.BMC Cancer. 2013 May 28;13:261.
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