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MIC1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • IF - MIC1 Antibody (N-term) AP11766a
    Confocal immunofluorescent analysis of MIC1 Antibody (N-term)(Cat#AP11766a) with MDA-MBA231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
    detail
  • WB - MIC1 Antibody (N-term) AP11766a
    MIC1 Antibody (N-term) (Cat. #AP11766a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the MIC1 antibody detected the MIC1 protein (arrow).
    detail
  • FC - MIC1 Antibody (N-term) AP11766a
    MIC1 Antibody (N-term) (Cat. #AP11766a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IF, FC, WB, E
Primary Accession Q96DM3
Other Accession NP_037458.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 74975 Da
Antigen Region 34-66 aa
Additional Information
Gene ID 29919
Other Names Uncharacterized protein C18orf8, Colon cancer-associated protein Mic1, Mic-1, C18orf8, MIC1
Target/Specificity This MIC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-66 amino acids from the N-terminal region of human MIC1.
Dilution IF~~1:10~50
WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMIC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RMC1 (HGNC:24326)
Synonyms C18orf8, MIC1, WDR98
Function Componement of the CCZ1-MON1 RAB7A guanine exchange factor (GEF). Acts as a positive regulator of CCZ1-MON1A/B function necessary for endosomal/autophagic flux and efficient RAB7A localization (PubMed:29038162).
Cellular Location Lysosome membrane. Late endosome membrane
Research Areas
Citations (0)
citation

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Background

C18orf8 is an uncharacterized protein.

References

Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 365.00
$ 140.00
Cat# AP11766a
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