SPECC1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IF, FC, IHC-P, WB, E |
---|---|
Primary Accession | Q69YQ0 |
Other Accession | Q2KN98, Q2KN93, Q2KN97, NP_001138940.1 |
Reactivity | Human, Mouse |
Predicted | Chicken, Zebrafish |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 124544 Da |
Antigen Region | 705-733 aa |
Gene ID | 23384 |
---|---|
Other Names | Cytospin-A, Renal carcinoma antigen NY-REN-22, Sperm antigen with calponin homology and coiled-coil domains 1-like, SPECC1-like protein, SPECC1L, CYTSA, KIAA0376 |
Target/Specificity | This SPECC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 705-733 amino acids from the Central region of human SPECC1. |
Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SPECC1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SPECC1L |
---|---|
Synonyms | CYTSA, KIAA0376 |
Function | Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration. |
Cellular Location | Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell junction, gap junction. Note=Colocalizes with acetylated alpha- tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center |
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Provided below are standard protocols that you may find useful for product applications.
Background
CYTSAis involved in cytokinesis and spindle organization.
References
Scanlan, M.J., et al. Int. J. Cancer 83(4):456-464(1999)
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