TLCD2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | A6NGC4 |
Other Accession | XP_001717074.2, NP_001157879.1, XP_001718182.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 28733 Da |
Antigen Region | 222-250 aa |
Gene ID | 727910 |
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Other Names | TLC domain-containing protein 2, TLCD2 |
Target/Specificity | This TLCD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-250 amino acids from the C-terminal region of human TLCD2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TLCD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TLCD2 |
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Function | Regulates the composition and fluidity of the plasma membrane (PubMed:30509349). Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (PubMed:30509349). Does not appear to have any effect on LCPUFA synthesis (PubMed:30509349). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
References
Pewzner-Jung, Y., et al. J. Biol. Chem. 281(35):25001-25005(2006)
Zody, M.C., et al. Nature 440(7087):1045-1049(2006)
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