Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
MYCBP Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q99417 |
| Other Accession | Q9EQS3, Q2TBP7, NP_036465.2 |
| Reactivity | Mouse |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 11967 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 26292 |
|---|---|
| Other Names | C-Myc-binding protein, Associate of Myc 1, AMY-1, MYCBP, AMY1 |
| Target/Specificity | This MYCBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MYCBP. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MYCBP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MYCBP (HGNC:7554) |
|---|---|
| Synonyms | AMY1 |
| Function | May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC. |
| Cellular Location | Cytoplasm. Nucleus. Mitochondrion. Note=Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1 |
| Tissue Location | Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The MYCBP gene encodes a protein that binds to the N-terminal region of MYC (MIM 190080) and stimulates the activation of E box-dependent transcription by MYC.
References
Xiong, J., et al. Oncogene 29(35):4980-4988(2010)
Wang, H.B., et al. J. Gastrointest. Surg. 14(8):1227-1234(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Sedoris, K.C., et al. Biochemistry 46(29):8659-8668(2007)
Ishizaki, R., et al. Genes Cells 11(8):949-959(2006)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
