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SERPINE2 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SERPINE2 Antibody (Center) AP12607c
    SERPINE2 Antibody (Center) (Cat. #AP12607c) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the SERPINE2 antibody detected the SERPINE2 protein (arrow).
    detail
  • IHC-P - SERPINE2 Antibody (Center) AP12607c
    SERPINE2 Antibody (Center) (Cat. #AP12607c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SERPINE2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession P07093
Other Accession NP_006207.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 44002 Da
Antigen Region 106-135 aa
Additional Information
Gene ID 5270
Other Names Glia-derived nexin, GDN, Peptidase inhibitor 7, PI-7, Protease nexin 1, PN-1, Protease nexin I, Serpin E2, SERPINE2, PI7, PN1
Target/Specificity This SERPINE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the Central region of human SERPINE2.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSERPINE2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SERPINE2
Synonyms PI7, PN1
Function Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Cellular Location Secreted, extracellular space.
Research Areas
Citations (0)
citation

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Background

SERPINE2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.

References

Bianchini, G., et al. J. Clin. Oncol. 28(28):4316-4323(2010)
Hersh, C.P., et al. Am. J. Respir. Crit. Care Med. 182(5):605-613(2010)
Hultman, K., et al. J. Neurosci. Res. 88(11):2441-2449(2010)
Kim, W.J., et al. Eur. Respir. J. (2010) In press :
Sorheim, I.C., et al. Clin Respir J 2 SUPPL 1, 129-131 (2008) :

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$ 182.50
$ 70.00
Cat# AP12607c
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