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CNRP1 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CNRP1 Antibody (Center) AP12679c
    Western blot analysis of lysate from human brain tissue lysate, using CNRP1 Antibody (Center)(Cat. #AP12679c). AP12679c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
    detail
  • IHC-P - CNRP1 Antibody (Center) AP12679c
    CNRP1 Antibody (Center) (Cat. #AP12679c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CNRP1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q96F85
Other Accession Q9GKT6, NP_056278.1, NP_001104571.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 18648 Da
Antigen Region 76-104 aa
Additional Information
Gene ID 25927
Other Names CB1 cannabinoid receptor-interacting protein 1, CRIP-1, CNRIP1, C2orf32
Target/Specificity This CNRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-104 amino acids from the Central region of human CNRP1.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCNRP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNRIP1
Synonyms C2orf32
Function [Isoform 1]: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.
Research Areas
Citations (0)
citation

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Background

This gene encodes a G-protein coupled receptor which interacts with the C-terminal tail of cannabinoid receptor 1. This receptor plays a role in synaptic plasticity, analgesia, appetite, and neuroprotection. Two transcript variants encoding different isoforms have been described for this gene.

References

Rose, J. Phd, et al. Mol. Med. (2010) In press :
Gieger, C., et al. PLoS Genet. 4 (11), E1000282 (2008) :
Niehaus, J.L., et al. Mol. Pharmacol. 72(6):1557-1566(2007)
Swick, L., et al. J. Neurochem. 97(5):1447-1455(2006)

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$ 365.00
$ 140.00
Cat# AP12679c
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