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SYTL1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IYJ3 |
| Other Accession | NP_001180237.1, NP_116261.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 61857 Da |
| Antigen Region | 296-325 aa |
| Gene ID | 84958 |
|---|---|
| Other Names | Synaptotagmin-like protein 1, Exophilin-7, Protein JFC1, SYTL1, SLP1 |
| Target/Specificity | This SYTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human SYTL1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SYTL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SYTL1 |
|---|---|
| Synonyms | SLP1 |
| Function | May play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity). |
| Cellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side Note=Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes |
| Tissue Location | Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
SYTL1 may play a role in vesicle trafficking (By similarity). It binds phosphatidylinositol 3,4,5-triphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity).
References
Neumuller, O., et al. Blood 114(7):1396-1404(2009)
Holt, O., et al. Traffic 9(4):446-457(2008)
Schmid, M., et al. J. Leukoc. Biol. 81(4):907-915(2007)
Johnson, J.L., et al. Biochem. J. 391 (PT 3), 699-710 (2005) :
Catz, S.D., et al. Biochem. J. 367 (PT 3), 791-799 (2002) :
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