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OXA1L Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - OXA1L Antibody (C-term) AP12848b
    OXA1L Antibody (C-term) (Cat. #AP12848b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the OXA1L antibody detected the OXA1L protein (arrow).
    detail
  • FC - OXA1L Antibody (C-term) AP12848b
    OXA1L Antibody (C-term) (Cat. #AP12848b) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, WB, E
Primary Accession Q15070
Other Accession NP_005006.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 48520 Da
Antigen Region 361-390 aa
Additional Information
Gene ID 5018
Other Names Mitochondrial inner membrane protein OXA1L, Hsa, OXA1Hs, Oxidase assembly 1-like protein, OXA1-like protein, OXA1L
Target/Specificity This OXA1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-390 amino acids from the C-terminal region of human OXA1L.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOXA1L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OXA1L
Function Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein
Research Areas
Citations (0)
citation

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Background

OXA1L is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase.

References

Haque, M.E., et al. J. Biol. Chem. 285(45):34991-34998(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Haque, M.E., et al. J. Biol. Chem. 285(36):28353-28362(2010)
Sato, T., et al. J. Biol. Chem. 284(22):14819-14827(2009)
Stiburek, L., et al. J. Mol. Biol. 374(2):506-516(2007)

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$ 182.50
$ 70.00
Cat# AP12848b
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