ELAVL2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, FC, WB, E |
---|---|
Primary Accession | Q12926 |
Other Accession | Q7SZT7, O09032, Q61701, P26378, Q91584, Q60900, Q14576, Q91903, Q8CH84, Q60899, NP_001164666.1, NP_001164668.1, A0A0R4IEW8 |
Reactivity | Human, Mouse |
Predicted | Rat, Xenopus, Zebrafish |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 39504 Da |
Antigen Region | 156-184 aa |
Gene ID | 1993 |
---|---|
Other Names | ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB |
Target/Specificity | This ELAVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human ELAVL2. |
Dilution | WB~~1:2000 IHC-P~~1:100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ELAVL2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ELAVL2 |
---|---|
Synonyms | HUB |
Function | RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs (By similarity). Seems to recognize a GAAA motif (By similarity). Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR (By similarity). |
Tissue Location | Brain; neural-specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene.
References
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)
Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) :
D'Alessandro, V., et al. Cell. Oncol. 30(4):291-297(2008)
Jonson, L., et al. Mol. Cell Proteomics 6(5):798-811(2007)
Yano, M., et al. J. Biol. Chem. 280(13):12690-12699(2005)
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