MKL2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9ULH7 |
Other Accession | P59759, NP_054767.3 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 118127 Da |
Antigen Region | 72-101 aa |
Gene ID | 57496 |
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Other Names | MKL/myocardin-like protein 2, Megakaryoblastic leukemia 2, Myocardin-related transcription factor B, MRTF-B, MKL2, KIAA1243, MRTFB |
Target/Specificity | This MKL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human MKL2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MKL2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MRTFB (HGNC:29819) |
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Function | Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
MKL2 acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.
References
Huang, D., et al. Genes Chromosomes Cancer 49(9):810-818(2010)
Holt, R., et al. Eur. J. Hum. Genet. 18(9):1013-1019(2010)
Medjkane, S., et al. Nat. Cell Biol. 11(3):257-268(2009)
Lagna, G., et al. J. Biol. Chem. 282(51):37244-37255(2007)
Morita, T., et al. J. Cell Biol. 179(5):1027-1042(2007)
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