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Bcl-G BH3 Domain Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9BZR8 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36598 Da |
| Antigen Region | 194-229 aa |
| Gene ID | 79370 |
|---|---|
| Other Names | Apoptosis facilitator Bcl-2-like protein 14, Bcl2-L-14, Apoptosis regulator Bcl-G, BCL2L14, BCLG |
| Target/Specificity | This Bcl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-229 amino acids from human Bcl. |
| Dilution | WB~~1:2000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Bcl-G BH3 Domain Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BCL2L14 |
|---|---|
| Synonyms | BCLG |
| Function | Plays a role in apoptosis. |
| Cellular Location | Cytoplasm. [Isoform 2]: Endomembrane system. Note=Predominantly localized to cytosolic organelles |
| Tissue Location | Isoform 1 is widely expressed. Isoform 2 is testis- specific. |
Provided below are standard protocols that you may find useful for product applications.
Background
Bcl-G belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of Bcl-G has been shown to induce apoptosis in cells.
References
Ozalp, S.S., et al., Eur J Gynaecol Oncol 23(5):419-422 (2002).
Guo, B., et al., J. Biol. Chem. 276(4):2780-2785 (2001).
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