TM9SF2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q99805 |
Other Accession | NP_004791.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 75776 Da |
Antigen Region | 111-140 aa |
Gene ID | 9375 |
---|---|
Other Names | Transmembrane 9 superfamily member 2, p76, TM9SF2 |
Target/Specificity | This TM9SF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the N-terminal region of human TM9SF2. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TM9SF2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TM9SF2 |
---|---|
Function | In the intracellular compartments, may function as a channel or small molecule transporter. |
Cellular Location | Endosome membrane; Multi-pass membrane protein. Golgi outpost {ECO:0000250|UniProtKB:Q66HG5}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q66HG5}. Note=Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation. {ECO:0000250|UniProtKB:Q66HG5} |
Tissue Location | Ubiquitously expressed. Especially abundant in pancreas, highly expressed in kidney, lower levels in heart, brain, skeletal muscle and placenta. Lowest expression in lung and liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
In the intracellular compartments, may function as a channel or small molecule transporter.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Dunham, A., et al. Nature 428(6982):522-528(2004)
Schimmoller, F., et al. Gene 216(2):311-318(1998)
Diaz, E., et al. J. Cell Biol. 138(2):283-290(1997)
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