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SSR2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SSR2 Antibody (C-term) AP13170b
    SSR2 Antibody (C-term) (Cat. #AP13170b) western blot analysis in human placenta tissue and Jurkat,Hela,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SSR2 antibody detected the SSR2 protein (arrow).
    detail
  • IHC-P - SSR2 Antibody (C-term) AP13170b
    SSR2 Antibody (C-term) (Cat. #AP13170b)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SSR2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • FC - SSR2 Antibody (C-term) AP13170b
    SSR2 Antibody (C-term) (Cat. #AP13170b) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession P43308
Other Accession Q5E9E4, NP_003136.1
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 20135 Da
Antigen Region 154-183 aa
Additional Information
Gene ID 6746
Other Names Translocon-associated protein subunit beta, TRAP-beta, Signal sequence receptor subunit beta, SSR-beta, SSR2, TRAPB
Target/Specificity This SSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the C-terminal region of human SSR2.
Dilution WB~~1:1000
IHC-P~~1:10~50
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSSR2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SSR2
Synonyms TRAPB
Function TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein
Research Areas
Citations (0)
citation

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Background

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq].

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Sikorska, M., et al. J. Neurosci. Res. 86(8):1680-1693(2008)
Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003)
Wang, L., et al. FEBS Lett. 457(3):316-322(1999)
Dodson, G., et al. Curr. Opin. Struct. Biol. 8(2):189-194(1998)

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$ 182.50
$ 70.00
Cat# AP13170b
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