RTDR1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q9UHP6 |
Other Accession | NP_055248.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 38592 Da |
Antigen Region | 17-45 aa |
Gene ID | 27156 |
---|---|
Other Names | Rhabdoid tumor deletion region protein 1, RTDR1 |
Target/Specificity | This RTDR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human RTDR1. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RTDR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RSPH14 (HGNC:13437) |
---|---|
Synonyms | RTDR1 |
Function | Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia. |
Cellular Location | Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q9D3W1} |
Tissue Location | Expressed in adult cerebellum, spinal cord, spleen, skeletal muscle and some/5 out of 9 rhabdoid tumors. Detected in fetal brain, lung, liver and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein with no known function but with slight similarity to a yeast vacuolar protein. The gene is located in a region deleted in pediatric rhabdoid tumors of the brain, kidney and soft tissues, but mutations in this gene have not been associated with the disease.
References
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Zhou, J., et al. Gene 241(1):133-141(2000)
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