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RTDR1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RTDR1 Antibody (N-term) AP13240a
    RTDR1 Antibody (N-term) (Cat. #AP13240a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RTDR1 antibody detected the RTDR1 protein (arrow).
    detail
  • IHC-P - RTDR1 Antibody (N-term) AP13240a
    RTDR1 Antibody (N-term) (Cat. #AP13240a)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RTDR1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q9UHP6
Other Accession NP_055248.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 38592 Da
Antigen Region 17-45 aa
Additional Information
Gene ID 27156
Other Names Rhabdoid tumor deletion region protein 1, RTDR1
Target/Specificity This RTDR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human RTDR1.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRTDR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RSPH14 (HGNC:13437)
Synonyms RTDR1
Function Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia.
Cellular Location Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q9D3W1}
Tissue Location Expressed in adult cerebellum, spinal cord, spleen, skeletal muscle and some/5 out of 9 rhabdoid tumors. Detected in fetal brain, lung, liver and kidney.
Research Areas
Citations (0)
citation

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Background

This gene encodes a protein with no known function but with slight similarity to a yeast vacuolar protein. The gene is located in a region deleted in pediatric rhabdoid tumors of the brain, kidney and soft tissues, but mutations in this gene have not been associated with the disease.

References

Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Zhou, J., et al. Gene 241(1):133-141(2000)

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$ 182.50
$ 70.00
Cat# AP13240a
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