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CDH22 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CDH22 Antibody (Center) AP13244c
    CDH22 Antibody (Center) (Cat. #AP13244c) western blot analysis in HepG2,293,K562 cell line lysates (35ug/lane).This demonstrates the CDH22 antibody detected the CDH22 protein (arrow).
    detail
  • IHC-P - CDH22 Antibody (Center) AP13244c
    CDH22 Antibody (Center) (Cat. #AP13244c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CDH22 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q9UJ99
Other Accession NP_067071.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 89091 Da
Antigen Region 411-440 aa
Additional Information
Gene ID 64405
Other Names Cadherin-22, Pituitary and brain cadherin, PB-cadherin, CDH22, C20orf25
Target/Specificity This CDH22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 411-440 amino acids from the Central region of human CDH22.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDH22 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDH22
Synonyms C20orf25
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)
citation

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Background

This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs.

References

Lewis, J.P., et al. Genomics (2010) In press :
Liu, Y., et al. Cancer Biol. Ther. 8(14):1352-1359(2009)
Zhou, J., et al. Tumour Biol. 30(3):130-140(2009)
Bento, J.L., et al. Genomics 92(4):226-234(2008)
Wu, J., et al. J. Endocrinol. 176(3):381-391(2003)

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$ 182.50
$ 70.00
Cat# AP13244c
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