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KCTD3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9Y597 |
| Other Accession | NP_057205.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 88984 Da |
| Antigen Region | 725-754 aa |
| Gene ID | 51133 |
|---|---|
| Other Names | BTB/POZ domain-containing protein KCTD3, Renal carcinoma antigen NY-REN-45, KCTD3 |
| Target/Specificity | This KCTD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 725-754 amino acids from the C-terminal region of human KCTD3. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KCTD3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KCTD3 |
|---|---|
| Function | Accessory subunit of potassium/sodium hyperpolarization- activated cyclic nucleotide-gated channel 3 (HCN3) up-regulating its cell-surface expression and current density without affecting its voltage dependence and kinetics. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q8BFX3}. |
| Tissue Location | Broadly expressed in normal tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KCTD3 belongs to the KCTD3 family. It contains one BTB (POZ) domain and five WD repeats. The exact function of KCTD3 is not known. There are three named isoforms.
References
Lehner, B., et al. Genome Res. 14(7):1315-1323(2004)
Scanlan, M.J., et al. Int. J. Cancer 83(4):456-464(1999)
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