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UPRT Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q96BW1 |
| Other Accession | Q95KB0, Q5ZIJ8, Q32LA4, NP_659489.1 |
| Reactivity | Mouse |
| Predicted | Bovine, Chicken, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 33786 Da |
| Antigen Region | 204-233 aa |
| Gene ID | 139596 |
|---|---|
| Other Names | Uracil phosphoribosyltransferase homolog, UPRT |
| Target/Specificity | This UPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-233 amino acids from the C-terminal region of human UPRT. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UPRT Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UPRT |
|---|---|
| Cellular Location | Cytoplasm. Nucleus |
| Tissue Location | Highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.
References
Zhao, F.J., et al. Prostate Cancer Prostatic Dis. 12(2):166-171(2009)
Li, J., et al. J. Hum. Genet. 52(5):415-422(2007)
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