DPYSL3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q14195 |
Other Accession | Q62952, Q62188, NP_001378.1 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 61963 Da |
Antigen Region | 461-490 aa |
Gene ID | 1809 |
---|---|
Other Names | Dihydropyrimidinase-related protein 3, DRP-3, Collapsin response mediator protein 4, CRMP-4, Unc-33-like phosphoprotein 1, ULIP-1, DPYSL3, CRMP4, DRP3, ULIP, ULIP1 |
Target/Specificity | This DPYSL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 461-490 amino acids from the C-terminal region of human DPYSL3. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DPYSL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DPYSL3 |
---|---|
Synonyms | CRMP4, DRP3, ULIP, ULIP1 |
Function | Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity). |
Cellular Location | Cytoplasm. Cell projection, growth cone. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. |
Tissue Location | Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord |
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Provided below are standard protocols that you may find useful for product applications.
Background
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
References
Okita, K., et al. Cancer Sci. 101(11):2333-2340(2010)
Gao, X., et al. Oncogene 29(32):4555-4566(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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