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DPYSL3 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - DPYSL3 Antibody (C-term) AP14234b
    Western blot analysis of DPYSL3 (arrow) using rabbit polyclonal DPYSL3 Antibody (C-term) (Cat. #AP14234b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DPYSL3 gene.
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  • WB - DPYSL3 Antibody (C-term) AP14234b
    Anti-DPYSL3 Antibody (C-term) at 1:1000 dilution + human fetal brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 62 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • IHC-P - DPYSL3 Antibody (C-term) AP14234b
    DPYSL3 Antibody (C-term) (AP14234b)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DPYSL3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q14195
Other Accession Q62952, Q62188, NP_001378.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 61963 Da
Antigen Region 461-490 aa
Additional Information
Gene ID 1809
Other Names Dihydropyrimidinase-related protein 3, DRP-3, Collapsin response mediator protein 4, CRMP-4, Unc-33-like phosphoprotein 1, ULIP-1, DPYSL3, CRMP4, DRP3, ULIP, ULIP1
Target/Specificity This DPYSL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 461-490 amino acids from the C-terminal region of human DPYSL3.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDPYSL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DPYSL3
Synonyms CRMP4, DRP3, ULIP, ULIP1
Function Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
Cellular Location Cytoplasm. Cell projection, growth cone. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
Tissue Location Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord
Research Areas
Citations (0)
citation

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Background

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).

References

Okita, K., et al. Cancer Sci. 101(11):2333-2340(2010)
Gao, X., et al. Oncogene 29(32):4555-4566(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 182.50
$ 70.00
Cat# AP14234b
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