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IL32 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P24001 |
| Other Accession | NP_001012650.1, NP_001012649.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26676 Da |
| Antigen Region | 24-53 aa |
| Gene ID | 9235 |
|---|---|
| Other Names | Interleukin-32, IL-32, Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32, NK4, TAIF |
| Target/Specificity | This IL32 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human IL32. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | IL32 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IL32 |
|---|---|
| Synonyms | NK4, TAIF |
| Function | Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. |
| Cellular Location | Secreted. |
| Tissue Location | Selectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
References
Li, W., et al. J. Immunol. 185(9):5056-5065(2010)
Cho, K.A., et al. Microb. Pathog. 49(3):95-104(2010)
Kobori, A., et al. World J. Gastroenterol. 16(19):2355-2361(2010)
Yue, D., et al. Asian J. Androl. 12(3):381-389(2010)
Chae, J.I., et al. Cell. Immunol. 264(1):47-53(2010)
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